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Troponin certain to heparin leads to reduced calculated troponin plasma focus in comparison to serum.[seventy six] Other sources of interference which could influence the assay detection course of action and trigger Wrong-negative troponin values include ascorbic acid in immunoenzymometric assays employing alkaline phosphatase, biotin in assays utilizing a biotinylated antibody, streptokinase within the existence of streptavidin, and large titers of antibodies to ruthenium or streptavidin in cTnT assays.

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